Second harmonic generation (SHG),
a nonlinear optical tool, was used to
characterize DNA bound through a
chemical linker to the flat surface of a
hemispherical lens. Contact angle
measurements were used to guarantee
that the chemical linker did not hydrolyze
under experimental conditions. SHG
experiments followed the effects of salt...
The macroscale mechanical and physical properties of materials are inherently linked to the underlying microstructure. Traditional continuum mechanics theories have focused on approximating the heterogeneous microstructure as a continuum, which is conducive to a partial differential equation mathematical description. Although this makes large scale simulation of material much more efficient...
Although non-viral gene therapy has great potential for use in the lung, several problems including inefficient gene transfer and expression and the relative lack of cell-specific targeting have limited its applications. The two approaches that have been used to target genes to desired cell types are through specific ligand-receptor interactions...
Middle childhood is an important but often overlooked developmental period. Similarly, a large literature examines the importance of child care as a developmental context, focusing almost exclusively on pre-school child care experiences. Through three related empirical studies, this dissertation aims to address these two gaps in the extant literature. These...
This dissertation addresses questions in the fields of household finance and corporate finance. In Chapter 1, I use a quasi-experiment in Norway to examine how households respond to capital taxation. The introduction of a new wealth assessment methodology in 2010 led to geographic discontinuities in household exposure to wealth taxes,...
Saccades are rapid eye movements that bring visual images into focus by placing them on the fovea. The control of accurate and precise saccades is essential for normal visual perception of the world around us. Disruptions in saccade production are the hallmark of several neurological disorders such as schizophrenia and...
This final report contains information on years 6-7-8 (2004-2007) of TEA-21 funded projects designated A487, W420, and A212. The report was submitted by Morris E. Fine and Semyon Vaynman in 2007.
This manual describes use of a new hybrid autonomous crack and structural response monitoring (ACSM) system. It is designed as a low cost alternative to the research grade version employing SOMAT’s eDAQ data recording system. The concept is to combine a new field portable, 24 bit, 12 channel seismograph with...
In urban areas, an accurate evaluation of ground deformations from various construction activities requires one to properly consider both the probable ground strain level under expected working conditions and the recent stress history of the soil. For well-designed projects, the levels of ground strains typically are less than 0.5%, emphasizing...
Cells are known to respond to external stimuli such as chemical, physical and mechanical cues from their microenvironments. In this work, we developed the technology to to complement the previously reported studies that deal with substrates' mechanical property by developing thin polydimethlysiloxane (PDMS) membrane microdevices using microfabrication technology. Typically, multiples...