Index Catalog // Arch : Northwestern University Institutional Repository

Description:: PRC is a PGC-1 coactivator family member responsive to serum growth factors and up regulated in proliferating cells. Unlike PGC-1α and PGC-1β, PRC has not been studied extensively and and its function or regulation remains largely unknown. Both PGC-1α and PGC-1β have been shown to be important regulators of mitochondrial...
Keyword:: Biochemistry and Chemical
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Kristel Vercauteren
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/02/2018
Date Modified:: 10/02/2018
Date Created:: 2008-12-08
Resource Type:: Dissertation

Description:: Kinesin-1 is a motor protein that transports cargo along microtubules. Inside cells, the majority of kinesin-1 is regulated to conserve ATP and ensure its proper intracellular distribution and coordination with other motors. Regulated kinesin-1 is folded in half, and interactions between coiled-coil regions near the N-terminal enzymatically active heads and...
Keyword:: kinesin and regulation
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Kristen Dietrich
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/14/2018
Date Modified:: 09/14/2018
Date Created:: 2008-11-04
Resource Type:: Dissertation

Description:: A tetramer model for HIV-1 Integrase (IN) with DNA representing the LTR termini was previously assembled which predicted amino acid residues on the enzyme surface that interact with the LTR termini (Chen et al, 2006). A separate structural alignment of HIV-1, SIV, and ASV INs predicted which of these residues...
Keyword:: HIV, DNA, model structure, and Integrase
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: James Robert Dolan
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/14/2018
Date Modified:: 09/14/2018
Date Created:: 2008-08-27
Resource Type:: Dissertation

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