Northwestern University

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The Role of a Guanine Quadruplex and Associated sRNA in Pilin Antigenic Variation of Neisseria gonorrhoeae

Description:

Neisseria gonorrhoeae (Ng), a strict human pathogen, is the sole causative agent of gonorrhea. Gc possess a complex gene conversion system, the pilin antigenic variation system, (pilin Av), which alters the DNA sequence of the major pilin, PilE. Pilin Av results in the constant alteration of the surface exposed appendage,...

Keyword:

DNA recombination, Antigenic variation, and Guanine Quadruplex

Subject:

Microbiology and Genetics

Creator:

Prister, Lauren Leigh

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_684526 and http://dissertations.umi.com/northwestern:14798