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Filtering by: Date created tesim 1/1/2018 Subject Cellular biology

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Redox Homeostasis In the Skin: Peroxiredoxin 1 Promotes the Stability of a Pro-Differentiation Cadherin Desmoglein 1

Description:

Desmosomes, complex structures found at intercellular junctions, are important for the development, structural integrity, and immune barrier of the skin. Extracellular components of the desmosome connect neighboring cells and intracellular interactions amongst cadherin, armadillo, and plakin proteins anchor the desmosome to intermediate filaments. Beyond their canonical role as “spot welds”...

Subject:

Health sciences and Cellular biology

Creator:

Lee, Sherry

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

04/28/2020

Date Created:

2018-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_572406 and http://dissertations.umi.com/northwestern:14076
The Role of Desmoglein-1 in Epidermal Stratification via Retromer-mediated Recycling and Actin Regulation

Description:

Desmosomal cadherins are a recent evolutionary innovation that make up the adhesive core of highly specialized intercellular junctions called desmosomes. Desmosomal cadherins, desmogleins and desmocollins, are related to the classical cadherins but their cytoplasmic domains are tailored for anchoring intermediate filaments instead of actin to sites of cell-cell adhesion. The...

Keyword:

Keratinocyte, Desmosome, Retromer chaperone, Dsg1, SAM syndrome, and Endosomal trafficking

Subject:

Cellular biology

Creator:

Hegazy, Marihan

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_944940 and http://dissertations.umi.com/northwestern:16344

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Redox Homeostasis In the Skin: Peroxiredoxin 1 Promotes the Stability of a Pro-Differentiation Cadherin Desmoglein 1

The Role of Desmoglein-1 in Epidermal Stratification via Retromer-mediated Recycling and Actin Regulation

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