Northwestern University

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Dynamic Mechanisms of Metabotropic Glutamate Receptor Activation and Modulation

Description:

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors in humans and play a role in nearly all physiological processes. Among GPCRs, metabotropic glutamate receptors (mGluRs) are a structurally distinct family of synaptic receptors that are essential in regulating neurotransmission and synaptic plasticity. Due to their important regulatory...

Keyword:

structural dynamics, mGluRs, conformational dynamics, membrane proteins, smFRET, and GPCRs

Subject:

Pharmacology, Biochemistry, and Biophysics

Creator:

Liauw, Brandon Wey-Hung

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_937523 and http://dissertations.umi.com/northwestern:16310