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Poly-pathway effects of dopamine covered iron oxide core - titanium dioxide shell nanoparticles

Description:

This thesis proposes a robust multi-pronged approach to study the effect of nanoparticles on cells. In the first place, this work is focused on investigation of the protein corona that accumulates on the surface of nanoparticles internalized by the cells and their poly-pathway effects on protein availability and messenger RNA...

Keyword:

PARP, Nanoparticles, BIRC5, XFM, and SR-FTIR

Subject:

Nanotechnology, Biology, and Biochemistry

Creator:

Lastra, Ruben Omar

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

10/07/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_837951 and http://dissertations.umi.com/northwestern:15671
Structure-Activity Relationships in the Biological Interactions of Spherical Nucleic Acids

Description:

Nucleic acid drugs promise to revolutionize the development of therapeutics. They offer a platform for digital medicine, where systematic changes to the nucleic acid sequence can be utilized to target the entire human genome. However, nucleic acids suffer from a number of drawbacks, such as negligible cellular uptake and rapid...

Keyword:

siRNA, Spherical Nucleic Acids, and High Throughput Analysis

Subject:

Nanotechnology, Nanoscience, and Biochemistry

Creator:

Yamankurt, Gokay

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

04/29/2020

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14982 and etdadmin_upload_717353

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Poly-pathway effects of dopamine covered iron oxide core - titanium dioxide shell nanoparticles

Structure-Activity Relationships in the Biological Interactions of Spherical Nucleic Acids

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