Importance: Despite its efficacy, low tidal volume ventilation (LTVV) remains severely underutilized for patients with acute respiratory distress syndrome (ARDS). Physician under-recognition of ARDS is a significant barrier to LTVV use. We propose a computational method that addresses some of the limitations of the current approaches to automated measurement of...
Cell state transitions are often triggered by large changes in the
concentrations of transcription factors and therefore large differences
in their stoichiometric ratios. Whether cells can elicit transitions using
modest changes in the ratios of co-expressed factors is unclear. Here,
we investigate how cells in the Drosophila eye resolve state...
Pediatric participants performed a series of trials that involved stepping up onto a raised platform. Body weight load was modulated during this task from -20% to +15% in 5% increments (excluding -5%). Outcome measures include peak hip abduction moments, peak support moments, and individual hip, knee, and ankle percent contributions...
Learning to discriminate between different sensory stimuli is essential for survival. In rodents, the olfactory bulb, which contributes to odor discrimination via pattern separation, exhibits extensive structural synaptic plasticity involving the formation and removal of synaptic spines, even in adult animals. The network connectivity resulting from this plasticity is...
A noncomprehensive list of large urban fires in the 1850s United States. All fires were large enough to destroy 20 structures or do $200,000 in damage (in 1850s dollars). Some fires are included on the basis of verbal descriptions (e.g., "downtown destroyed") that suggest that the fires were of this...
Data in support of the manuscript titled "Humans Exploit the Trade-Off Between Mediolateral Stability and Manoeuvrability During Walking".
Abstract:
People use the mechanical interplay between stability and manoeuvrability to successfully walk. During single limb support, body states (position and velocity) that increase lateral stability will inherently resist lateral manoeuvres, decrease...