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Description:: It is pertinent now more than ever that we find sustainable alternatives to produce chemicals. For decades, scientists and engineers have turned to biological systems to help meet societal needs in energy, medicine, materials, and moreespecially when chemical synthesis is untenable. Often, biologically-produced small molecules are insufficient for production at...
Keyword:: metabolic engineering, biotechnology, cell-free systems, biosynthetic pathway, synthetic biology, and enzymatic reactions
Subject:: Chemical and Biological Engineering
Creator:: Ashty Karim
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/14/2019
Date Modified:: 11/20/2019
Date Created:: 2018-01-01
Resource Type:: Dissertation

Description:: Metabolic engineering of microorganisms to produce useful compounds from renewable substrates is a promising means for sustainable, on-demand production of chemicals. However, efforts to design and engineer microbial cell factories are constrained by costly and slow “build” times in which each genetic variation requires re-engineering a new strain for each...
Keyword:: metabolic engineering, cell-free, synthetic biology, prototyping, and limonene
Subject:: Chemical and Biological Engineering
Creator:: Quentin Merle Dudley
Owner:: Scholarly Digital Publishing
Date Uploaded:: 01/25/2019
Date Modified:: 01/30/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: There is a need for alternative biomanufacturing solutions to produce novel medicines and help solve long-standing issues regarding difficult-to-treat diseases. Cell-free protein synthesis (CFPS) provides scientists with a new paradigm for producing proteins with an unprecedented freedom and control over the biomolecular machinery involved. In this document, I describe my...
Keyword:: antibodies, genome engineering, non-canonical amino acid, synthetic biology, and Cell-free protein synthesis
Subject:: Chemical and Biological Engineering
Creator:: Rey William Martin
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/21/2018
Date Modified:: 10/21/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

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