Stroke is the leading cause of permanent adult disability. Subcortical unilateral (hemiparetic) stroke affecting the internal capsule or basal ganglia is the most common of all strokes and usually results in hemiparesis of the contralateral arm and leg. About 80% of the individuals with a moderate to severe hemiparetic stroke...
Following a stroke, precise, individuated control of single joints is often replaced by highly stereotyped patterns of multi-joint movement, due to a loss of independent joint control, which can negatively impact functional use of the paretic arm. Despite the debilitating nature of this impairment, the precise underlying neural mechanisms remain...