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Filtering by: Keyword spherical nucleic acids Keyword surface modification Resource type Dissertation

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Description:: Oligonucleotides can be used to modulate the regulation of pathological genes that are associated with various diseases. However, due to biological barriers, efficient delivery of oligonucleotides, especially to extrahepatic tissues, remains a challenge. To overcome these barriers, multiple delivery strategies have been developed, ranging from medicinal chemistry to nanotechnology. Nanoparticle-based...
Keyword:: surface modification, biodistribution, and spherical nucleic acids
Subject:: Chemistry
Creator:: Zhang, Wuliang
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 10/07/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_830130 and http://dissertations.umi.com/northwestern:15627

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