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Modeling Cell Protrusion by a Population of Actin Filaments

Description:

Actin polymerization is responsible for the protrusion of filopodia and lamellipodia in immune, cancer, and other motile cells, as well as for propulsion of some intra cellular pathogens. Protrusion of a lamellipodium by the very filaments supporting the membrane load operates by the Brownian ratchet mechanism, with overall organization governed...

Keyword:

simulation, energetics, protrusion, actin, lamellipodium, and stochastic

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Thomas Schaus

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/30/2018

Date Modified:

08/30/2018

Date Created:

2007-12-10

Resource Type:

Dissertation