Northwestern University

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The Perinucleolar Compartment: Studies on Function and Development as a Novel Pan-cancer and Drug Discovery Marker

Description:

The perinucleolar compartment is a nuclear substructure that is associated with, but structurally distinct from the nucleolus. Previous studies have shown that the PNC preferentially forms in cancer cells and PNC prevalence (% of non-mitotic and non-apoptotic cells in a population with one or more PNC) is a prognostic in...

Keyword:

anti-cancer drug, prognostic marker, Perinucleolar comparment, and metastasis

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

John Thomas Norton

Owner:

Jason Christ Chandra

Date Uploaded:

08/30/2018

Date Modified:

08/30/2018

Date Created:

2007-12-10

Resource Type:

Dissertation