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Immunomodulatory Receptors in Herpes Simplex Virus Pathogenesis

Description:

Herpes simplex virus (HSV) is a ubiquitous human pathogen capable of causing debilitating diseases such as herpes stromal keratitis (HSK) and herpes simplex encephalitis (HSE). Although HSV infection initiates disease pathogenesis, the resulting clinical manifestations are attributed to immunopathological events that occur following viral clearance. To elucidate the molecular mechanisms...

Keyword:

herpes stromal keratitis, herpes simplex encephalitis, herpes simplex virus, herpesvirus entry mediator, and TAM receptors

Subject:

Virology and Immunology

Creator:

Park, Seo Jin

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

10/07/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_844174 and http://dissertations.umi.com/northwestern:15730
Herpes Virus Entry Mediator (HVEM) and Ocular Herpes: More Than Meets the Eye

Description:

Herpes stromal keratitis (HSK) is a potentially blinding inflammatory condition initiated by corneal infection with herpes simplex virus (HSV). As its name suggests, the host receptor herpes virus entry mediator (HVEM) facilitates HSV entry through interactions with a viral envelope glycoprotein. HVEM also bridges several signaling networks, binding ligands from...

Keyword:

herpes stromal keratitis, herpes simplex virus, immunopathology, inflammation, and cornea

Subject:

Life Sciences

Creator:

Rebecca Giovanna Edwards

Owner:

Scholarly Digital Publishing

Date Uploaded:

02/21/2018

Date Modified:

02/21/2018

Date Created:

2016-01-01

Resource Type:

Dissertation

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Immunomodulatory Receptors in Herpes Simplex Virus Pathogenesis

Herpes Virus Entry Mediator (HVEM) and Ocular Herpes: More Than Meets the Eye

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