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Nucleosome Positioning Effects on Cell-type Specificity and Gene Regulation in the Drosophila melanogaster Genome

Description:

In eukaryotic organisms, genomic DNA is organized and condensed into repeating arrays of nucleosomes. The histone protein octamer of each nucleosome wraps 147 base pairs of DNA, effectively restricting access by transcription factors and other regulatory proteins to that region. An additional histone, histone H1, binds the DNA outside the...

Keyword:

histone h1, mnase, genome, nucleosome, and drosophila

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Rebecca Martin

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/18/2018

Date Modified:

04/18/2018

Date Created:

2017-01-01

Resource Type:

Dissertation