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Filtering by: Keyword direct reprogramming Keyword spontaneous contraction Resource type Dissertation Subject Cellular biology

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1. Direct Reprogramming of Human Cells to a Cardiomyocyte-Like State

Description:: The reprogramming of somatic cells to a spontaneously contracting cardiomyocyte-like state using defined transcription factors has proven successful in mouse fibroblasts. However, this process has been less successful in human cells, thus limiting the potential clinical applicability of this technology in regenerative medicine. We hypothesized that this issue is due...
Keyword:: calcium cycling, spontaneous contraction, high-throughput, cardiomyocyte, direct reprogramming, and fibroblast
Subject:: Biology, Cellular biology, and Developmental biology
Creator:: Romero Tejeda, Marisol
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 05/31/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_970274 and http://dissertations.umi.com/northwestern:16446