Northwestern University

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Isocitrate Dehydrogenase 3 and One-Carbon Metabolism: Defining a Novel Role for Isocitrate Dehydrogenase 3 in Glioblastoma

Description:

Glioblastoma (GBM) is a highly malignant brain tumor that accounts for the most commonly diagnosed type of primary brain tumors in adults. It has a poor prognosis of only 15 months from the time of diagnosis. The gold standard therapy regimen consists of radiotherapy and the chemotherapeutic temozolomide. Both of...

Keyword:

Isocitrate Dehydrogenase, Glioblastoma, cancer, one-carbon metabolism, metabolism, and cytosolic serine hydroxymethyltransferase

Subject:

Cellular biology

Creator:

May, Jasmine Louise

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2018-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_593360 and http://dissertations.umi.com/northwestern:14231