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Topology Inspired Methods for the Design and Analysis of Transcriptomic Time-Series Data in Circadian Biology Research

Description:

Circadian rhythms — physiological, behavioral, and metabolic oscillations with an approximate 24-h period — are controlled by an evolutionarily conserved set of core clock genes operating at the transcriptional and protein level. Entrainable by Zeitgebers (external environmental stimuli such as light, temperature, and food) that modulate time-of-day specific functions, the...

Keyword:

Differential Dynamics Detection, Time-Series Analysis, Dynamical Systems Theory, Circadian Rhythms, Topological Analysis, and Cycle Detection

Subject:

Biostatistics, Applied mathematics, and Bioinformatics

Creator:

Ness-Cohn, Elan Meir

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_875611 and http://dissertations.umi.com/northwestern:15905