Northwestern University

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Filtering by: Keyword Sirtuin Resource type Dissertation

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Functional characterization of MnSOD and ACSS1 acetylation in metabolism and carcinogenesis

Description:

One of the fundamental observations in oncology is that the rate of cancer malignancy increases with age, which applies to most human malignancies including breast cancer. Therefore, it is crucial to elucidate the mechanistic connection between aging and carcinogenesis. The NAD+-dependent sirtuin family, specifically SIRT3, the primary mitochondrial deacetylase, which...

Keyword:

MnSOD, mitochondria, Sirtuin, cancer, ACSS1, and metabolism

Subject:

Biology

Creator:

Gao, Yucheng

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/28/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15526 and etdadmin_upload_815100