In nature, materials with complex architectures are formed through hierarchical self-assembly. Therefore, the study and design of hierarchically assembling materials is important in producing materials that mimic biological structures and is a key challenge in biomaterials science and engineering. In articular cartilage, hierarchical assembly of extracellular matrix (ECM) components provides...
Biomaterials have immense potential for studying fundamental biological processes and developing therapies to help regenerate or replace the structure and function of injured tissues. In order to accomplish this, they need to be designed to mimic the structure and function of Nature’s most important material, the extracellular matrix (ECM) surrounding...