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microRNA Regulation of Genes with Genetic Variation and their Systems-Level Consequences in Cancer

Description:

Gene regulatory networks contain multiple components including microRNAs (miRNAs) that coordinate regulation of genes to produce higher level cell functions. miRNAs are small non-coding RNA molecules that modulate gene expression post-transcriptionally by binding to short target motifs on mRNA transcripts to down-regulate target genes. Because miRNA regulation of genes is...

Keyword:

Gene Regulation, Systems Biology, Single Nucleotide Polymorphisms, Pathways, Cancer, and microRNAs

Subject:

Chemical and Biological Engineering

Creator:

Gary Wilk

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/21/2019

Date Modified:

10/21/2019

Date Created:

2018-01-01

Resource Type:

Dissertation