In the adult hippocampus of many mammalian species, populations of newborn dentate granule cells (DGCs) are continuously generated and undergo subsequent activity-dependent neuronal maturation and incorporation into the preexisting hippocampal circuitry. Increasing evidence has demonstrated that these young adult-born DGCs (abDGCs) participate in numerous cognitive and affective processes such as...
The planarian flatworm Schmidtea mediterranea is capable of recovery from nearly any injury, including regenerating an entire brain after decapitation, made possible by a pool of pluripotent stem cells which maintain all of the worm’s tissues into adulthood. However, the signals that control the production of new neurons in these...