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Microfluidic Platforms for Localized Electroporation mediated Cell Manipulation and Analysis

Description:

Biological experiments involving the manipulation and analysis of cells have always strived towards greater precision and resolution. Recent advances in micro and nanotechnology have improved the precision of manipulation and the resolution of analysis down to a single cell, thus opening new avenues of investigation. These advances have added a...

Keyword:

Intracellular Delivery, Microfluidics, and Localized Electroporation

Subject:

Bioengineering, Mechanical engineering, and Biophysics

Creator:

Mukherjee, Prithvijit

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15955 and etdadmin_upload_882743
Advancing the Delivery and Therapeutic Potential of Biologics with Spherical Nucleic Acids

Description:

The translation of proteins as effective intracellular drug candidates is limited by the challenge of cellular entry and their vulnerability to degradation. To advance their therapeutic potential, cell-impermeable proteins can be readily transformed into protein spherical nucleic acids (ProSNAs) or encapsulated into liposomal spherical nucleic acids (L-SNAs), structures defined by...

Keyword:

Intracellular Delivery, Enzyme, Spherical Nucleic Acid, Cancer Vaccine, Biologic, and Blood-Brain Barrier

Subject:

Chemistry

Creator:

Kusmierz, Caroline Danielle

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

10/07/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15666 and etdadmin_upload_837502

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Microfluidic Platforms for Localized Electroporation mediated Cell Manipulation and Analysis

Advancing the Delivery and Therapeutic Potential of Biologics with Spherical Nucleic Acids

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