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Filtering by: 2024-06-24 Keyword Egr Subject Integrated Graduate Program in the Life Sciences

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The Role of Early Growth Response Transcription Factors in Hematopoietic Development

Description:

The orderly process of hematopoietic differentiation is governed in large part by the coordinated transcription of specific genes. Deregulation of normal differentiation processes can lead to disease states including immunodeficiency, autoimmune disease, and leukemia. This research focuses on the family of transcription factors known as the early growth response (Egr)...

Keyword:

Egr, macrophage, transcription, and thymocyte

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

John Carter

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/12/2018

Date Modified:

09/12/2018

Date Created:

2008-05-09

Resource Type:

Dissertation
The role of early growth response transcriptional regulators in neurotrophin signaling and sympathetic nervous system development

Description:

Early growth response genes (Egr1-4) are induced as immediate early genes by a variety of extracellular stimuli that influence cellular growth and differentiation. Egr transcriptional regulators modulate gene expression by binding to Egr response elements (ERE) in target genes. In this study, the low affinity p75 neurotrophin receptor (p75NTR) was...

Keyword:

Egr, sympathetic nervous system, dnEgr, neurotrophin signaling, and p75NTR

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Xiaoguang Guo

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/02/2018

Date Modified:

08/02/2018

Date Created:

2007-05-31

Resource Type:

Dissertation

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The Role of Early Growth Response Transcription Factors in Hematopoietic Development

The role of early growth response transcriptional regulators in neurotrophin signaling and sympathetic nervous system development

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