Northwestern University

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Filtering by: Keyword DNA methylation Keyword RANK/RANKL pathway Keyword Tumor stem cell

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Interaction between DNA methylation and progesterone action during uterine leiomyoma stem cell development

Description:

Uterine leiomyoma (LM), the most common tumor of women, causes severe morbidity. LM cells can be separated into three molecularly and functionally distinct cell populations based on the expression pattern of CD34 and CD49b: stem (LSC, CD34+/CD49b+), intermediate (LIC, CD34+/CD49b-), and differentiated cells (LDC, CD34-/CD49b-). Progesterone via progesterone receptor (PR/PGR)...

Keyword:

RANK/RANKL pathway, Progesterone signaling, Tumor stem cell, DNA methylation, and Uterine leiomyoma

Subject:

Biology

Creator:

Liu, Shimeng

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

01/21/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15024 and etdadmin_upload_722143