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Elucidating the causes of heterogeneity in bacterial genome replication and conjugative transfer leveraging orthogonal transcriptional control

Description:

A disconnect exists between the behavior of transcriptional and genetic regulation in bacterial systems when comparing phenotypic patterns and dynamics of a population to those observed at the single cell level. In this thesis, we developed a number of tools and assays to better understand, overcome, and predict the challenges...

Keyword:

Synthetic Biology, Bacterial Signalling, Genomic Regulation, Conjugation, and Genomic Heterogeneity

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Andrew Hilz Scarpelli

Owner:

Scholarly Digital Publishing

Date Uploaded:

02/20/2018

Date Modified:

02/20/2018

Date Created:

2016-01-01

Resource Type:

Dissertation