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Dynamic transcription factor-mediated recruitment of genes to the nuclear pore complex in Saccharomyces cerevisiae.

Description:

In yeast, inducible genes such as INO1, PRM1 and HIS4 reposition from the nucleoplasm to nuclear periphery upon activation. This leads to a physical interaction with nuclear pore complex (NPC), interchromosomal clustering, and stronger transcription. Repositioning to the nuclear periphery is controlled by cis-acting transcription factor (TF) binding sites located...

Keyword:

Molecular biology and Cellular biology

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Carlo Randise-Hinchliff

Owner:

Scholarly Digital Publishing

Date Uploaded:

02/27/2018

Date Modified:

02/27/2018

Date Created:

2017-01-01

Resource Type:

Dissertation