Index Catalog // Arch : Northwestern University Institutional Repository

Description:: The ubiquitin-proteasome system degrades regulatory proteins and thereby controls a broad range of cellular processes such as the cell cycle, DNA-repair, gene transcription and signal transduction. The proteasome typically degrades its substrates completely into small peptides. However, biological exceptions do occur. For example, the activity of a handful of transcriptional...
Keyword:: Chemistry, Biology, and Cell
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Tian Lin
Owner:: Scholarly Digital Publishing
Date Uploaded:: 06/05/2018
Date Modified:: 06/05/2018
Date Created:: 2007-05-09
Resource Type:: Dissertation

Description:: Most women diagnosed with epithelial ovarian carcinoma (EOC) initially present with metastases, but little is known about the regulation of ovarian tumor cell dissemination by the tumor microenvironment. Because ovarian cancer cell dissemination is mostly limited to the peritoneal cavity and often results in the accumulation of malignant ascites, the...
Keyword:: Biology and Cell
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Jaime Symowicz
Owner:: Scholarly Digital Publishing
Date Uploaded:: 05/21/2018
Date Modified:: 05/21/2018
Date Created:: 2007-03-12
Resource Type:: Dissertation

Description:: Arsenic trioxide (As203) is an arsenic-derivative that exhibits potent growth inhibitory effects against malignant cells. The remarkable antitumor effects of As203 in vitro and in vivo have prompted the development of various clinical trials that established its activity in acute promyelocytic leukemia (APL). As203 is part of the standard treatment...
Keyword:: Biology, Cell, and Health Sciences
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Patrick Jang Yoon
Owner:: Scholarly Digital Publishing
Date Uploaded:: 05/21/2018
Date Modified:: 05/21/2018
Date Created:: 2007-03-12
Resource Type:: Dissertation

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