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Filtering by: Keyword C. elegans Keyword natural variation Resource type Dissertation

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Natural Genetic Variation Underlies Chemotherapeutic Drug Responses in Caenorhabditis elegans

Description:

Individuals within a species vary in complex phenotypes, such as responses to toxins. This drug-response variation causes patients who are treated with the same medicine to experience a range of side effects, ultimately decreasing the efficacy of some drugs. Particular genetic variants among individuals might contribute to differential drug responses,...

Keyword:

genetics, bleomycin, linkage mapping, natural variation, drug response, and C. elegans

Subject:

Biology

Creator:

Brady, Shannon Colleen

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14708 and etdadmin_upload_667842
Characterization and Applications of Natural Variation in C. elegans

Description:

Caenorhabditis elegans has been a highly productive model organism. However, most of the knowledge gained from the species has come a single strain isolated in Bristol, England in 1951. However, there exists significant potential in the natural variation present in the species to make discoveries. In this dissertation, I describe...

Keyword:

natural variation, pot-2, C. elegans, genomics, and telomeres

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Daniel Elwood Cook

Owner:

Scholarly Digital Publishing

Date Uploaded:

11/18/2019

Date Modified:

11/18/2019

Date Created:

2018-01-01

Resource Type:

Dissertation

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Natural Genetic Variation Underlies Chemotherapeutic Drug Responses in Caenorhabditis elegans

Characterization and Applications of Natural Variation in C. elegans

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