Understanding the chemical complexity of the extracellular matrix (ECM) and how chemical, biological, and physical cues bring changes to the behavior of cells has remained a grand challenge. Addressing these questions requires not only achieving systematic control over the interactions between cells and the ECM but also utilizing suitable analytical...
This dissertation demonstrates how related initiatives to reform narcotics laws and protect consumers from dangerous medicines – taking hold in the 1950s and institutionalized in the mid-1960s – created the foundation for a massive expansion of federal policing of illicit drugs. Centered on the history of the Food and Drug...
Introduction: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction associated with reduced quality of life, increased rates of depression and anxiety, and high economic burden to society and the individual. Current behavioral interventions, which target well-known symptom exacerbating factors such as catastrophizing and gastrointestinal- specific anxiety, have demonstrated...
Background: Evidence supporting a bidirectional relationship between depression and recurrent cardiovascular disease (CVD) appears strong, but there remains a need to better characterize the role of depression in CVD risk and cardiovascular health (CVH) promotion, especially in the context of comorbid risk factors such as cigarette smoking. In the present...
Seasonal malaria chemoprevention (SMC) was first recommended by the World Health Organization (WHO) in 2012 to prevent uncomplicated malaria in children and began implementation in Burkina Faso in 2014 under programmatic campaigns. Systematic assessment of the impact of national SMC campaigns requires data with weekly or monthly temporal resolution over...
Listeners can experience strong and often positive identification with music. Contemporary research has emphasized the importance of a listener’s own identity, including their sense of self and their desires, when forming such identifications. However, acknowledgments of the listener’s role in the listening experience have failed to productively engage discussions of...
In 2018, our ATRAP collaboration produced 5 trapped antihydrogen atoms per hour long trial. An apparatus with a Ioffe octupole trap and a faster magnet dump was used to confine and detect trapped antihydrogen atoms. This apparatus is unique in that four sideports spaced at 90 degrees from each other...
We consider general utility models and information structures of the agents and illustrate when economic conclusions for designing simple mechanisms in classical settings extends for general environments. We show that whether economic conclusions can be generalized depends on the details of the generalizations. For example, in single-item auction, competition and...
Recently, much public attention has been focused on racial inequalities in who is subjected to exclusionary school disciplinary policies, and consequently, forced to miss hours of instruction. Over the past two decades, researchers have documented the disparate impacts that zero-tolerance policies have had on students of color, low-income students, and...
Micro-X is a high-resolution X-ray spectroscopy sounding rocket mission that had its first flight in July 2018, becoming the first program to carry Transition-Edge Sensors (TES) and multiplexing Superconducting QUantum Interference Device (SQUID) readout electronics into space, successfully collect data, and subsequently recover the instruments. While a rocket pointing failure...