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Filtering by: Type Work Keyword Spherical Nucleic Acids

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Description:: The successful development of vaccines for triple negative breast cancer (TNBC) has been hindered because there are no identified tumor-associated antigens. As an alternative to peptide vaccines, the administration of tumor lysates has been investigated in TNBC to activate the immune system against tumors, wherein a mixture of tumor-specific lysates...
Keyword:: Medicine, Immunogenicity, Triple Negative Breast Cancer, Spherical Nucleic Acids, Immunology, Vaccination, Cancer Vaccines, and Drug Delivery
Subject:: Breast--Cancer
Creator:: Leah Broger
Owner:: Scholarly Digital Publishing
Date Uploaded:: 06/08/2020
Date Modified:: 07/23/2020
Date Created:: 2020-05-27
Resource Type:: Conference Proceeding

Description:: Nucleic acid drugs promise to revolutionize the development of therapeutics. They offer a platform for digital medicine, where systematic changes to the nucleic acid sequence can be utilized to target the entire human genome. However, nucleic acids suffer from a number of drawbacks, such as negligible cellular uptake and rapid...
Keyword:: siRNA, Spherical Nucleic Acids, and High Throughput Analysis
Subject:: Nanotechnology, Nanoscience, and Biochemistry
Creator:: Yamankurt, Gokay
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 04/29/2020
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:14982 and etdadmin_upload_717353

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