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Filtering by: Creator William H. Klein Resource type Article

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Characterization of Anti-ADDL Antibodies for Use in Tandem LSPR-MALDI Investigation of Alzheimber's Disease Brain Extracts

Description:

Small, soluble, self-assembling peptide Aβ-oligomers, known as ADDLs (amyloid-derived diffusible ligands), accumulate in the Alzheimer’s disease (AD) brain as Aβ 12-mers and are thought to contribute to AD neuropathological conditions. Unlike plaques, which were once thought to cause neuronal death due to insoluble amyloid plaque deposits, ADDLs initiate abnormal changes...

Keyword:

Volume 6

Creator:

Mary P. Lamber, Jessica M. Albasha, and William H. Klein

Owner:

Scholarly Digital Publishing

Date Uploaded:

07/23/2018

Date Modified:

07/23/2018

Date Created:

2009

Resource Type:

Article