Northwestern University

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Filtering by: Creator Scholtes, Gael Kaushik Keyword VHL

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Cellular Regulation of APOBEC3 Cytidine Deaminases by the Tumor Suppressor pVHL

Description:

Levels of the several different human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) cytidine deaminases vary across different cell types. While levels of nuclear-localized A3s are low or non-existent in primary cells, a nuclear A3 is often upregulated in cancer cells. Increased chromosomal mutagenesis due to nuclear A3...

Keyword:

VHL, HIV, Proteasome, and APOBEC

Subject:

Cellular biology

Creator:

Scholtes, Gael Kaushik

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/28/2021

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_822125 and http://dissertations.umi.com/northwestern:15598