Northwestern University

Parent Unit Name

Login

LIBRARIES | ARCH

Menu Search

Start Over

Filtering by: Creator Rodriguez, Yara Resource type Dissertation

1 entry found

List Gallery Masonry Slideshow

Identifying Potential Mechanisms of Enzalutamide Resistance in Prostate Cancer using a Genome-wide CRISPR activation Screen

Description:

Androgen receptor pathway inhibitors are the mainstay treatment for advanced prostate cancer, but resistance is common. Here, we used a CRISPR activation screen to identify genes that promote enzalutamide resistance in the metastatic castration-sensitive prostate cancer cell line LNCaP. We found that activation of the TGF-β target gene, PRRX2, promoted...

Subject:

Biology

Creator:

Rodriguez, Yara

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16015 and etdadmin_upload_898469