Northwestern University

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Filtering by: Creator Montauti, Elena Keyword Foxp3

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Foxp3-specific Deubiquitinase Modules enhance Treg fitness

Description:

Regulatory T (Treg) cells are required to control immune responses and maintain homeostasis, but are a significant barrier to antitumor immunity. Conversely, Treg instability, characterized by loss of the master transcription factor Foxp3 and acquisition of proinflammatory properties, can promote autoimmunity and/or facilitate more effective tumor immunity. A comprehensive understanding...

Keyword:

Tumor, Treg, Ubiquitin, Foxp3, Usp21, and Usp22

Subject:

Biology, Cellular biology, and Immunology

Creator:

Montauti, Elena

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/02/2022

Date Created:

2021-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_846345 and http://dissertations.umi.com/northwestern:15780