Northwestern University

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Filtering by: Creator Gangopadhyay, Anu Keyword Gout

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NLRP11 is Essential for NLRP3 Inflammasome Activation

Description:

Inflammasomes are intracellular multiprotein signaling complexes that link Pathogen Associated and Danger Associated Molecular Patterns (PAMPs and DAMPs) by Pattern Recognition Receptors (PRRs) to the activation of Caspase-1, leading to the secretion of pro-inflammatory cytokines interleukin (IL)-1β and IL-18, and the induction of pyroptosis. Nucleotide-binding oligomerization domain (NOD)-like containing a...

Keyword:

Inflammation, Inflammasome, Gout, Innate immune response, NLRP3, and NLRP11

Subject:

Biology

Creator:

Gangopadhyay, Anu

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

01/21/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15043 and etdadmin_upload_731489