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Filtering by: 2024-06-24 Creator Angela Kaye Pannier

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Engineering Substrate-Mediated Gene Delivery with Self-Assembled Monolayers and Soft Lithography

Description:

Substrate-mediated delivery involves the immobilization of DNA, complexed with nonviral vectors, to a biomaterial or surface that supports cell adhesion. Cells cultured on the substrate are exposed to elevated DNA concentrations within the local microenvironment, which enhances transfection. As surface properties are critical to this delivery approach, self-assembled monolayers (SAMs)...

Keyword:

Engineering

Subject:

Interdepartmental Biological Sciences Program

Creator:

Angela Kaye Pannier

Owner:

Scholarly Digital Publishing

Date Uploaded:

05/25/2018

Date Modified:

05/25/2018

Date Created:

2007-04-17

Resource Type:

Dissertation